Curriculum Vitae of Yigang Tong, PhD, Professor


Current position:

Director of Department of Omics and Bioinformatics

Professor of molecular microbiology

State Key Laboratory of Pathogen and Biosecurity

Beijing Institute of Microbiology and Epidemiology

Contact info:

20 Dong-Da Street, Fengtai District, Beijing 100071, China



B.S. Fudan University, China 1984-1988

M.S. Academy of Military Medical Science, China, 1988-1991

Ph.D. Academy of Military Medical Science, China, 1997-2000

PostDoc. University of British Columbia (UBC), Canada, 2003.3-2005.4

Field of Studies:

High throughput sequencing


Emerging infectious diseases



Brief Introduction:

Dr. Yigang Tong graduated from Fudan University and got his Ph.D degree in the Academy of Military Medical Sciences. He received postdoctoral training in the University of British Columbia (UBC), where he received Michael Smith Award. He is currently a professor in State Key Laboratory of Pathogen and Biosecurity. He has published more than 130 papers in international journals such as Nature, PNAS, Lance Infectious Disease, Journal of Virology, Journal of General Virology, Emerging Infectious Diseases, Journal of Biological Chemistry, etc. His major research interests are etiologic agents of emerging infectious diseases, high throughput sequencing techniques and bioinformatics approaches for novel pathogen identification and characterization, and bacteriophage. He has invented a PCR-based technique to clone full-length cDNA of multiple exon genes from blood cells without mRNA preparation and reverse transcription. He discovered that the high frequency reads in deep sequencing data represents the terminal sequences of the sequenced linear genome, which provide a cheap and convenient method for identification of bacteriophage genome termini. After the outbreak of Ebola Epidemic in West Africa, he went to Sierra Leone as the Chief Scientist with the Chinese Medical team. Besides the Ebola testing work, he and his team sequenced hundreds of Ebola samples and published the results on Nature (Nature 2015;524:93-6). An outbreak of piglet diarrhoea occurred in Guangdong Province in 2017, with the pathogen unknown. The research team used high-throughput sequencing technology to discover a new coronavirus, which was proven to originate from bats in Guangdong Province through source-tracing and evolution analysis. This research has been published in Nature magazine (Nature 2018; 556: 255-258).



  1. Zhou P, Fan H, Lan T, Yang XL, Shi WF, Zhang W, Zhu Y, Zhang YW, Xie QM, Mani S, Zheng XS, Li B, Li JM, Guo H, Pei GQ, An XP, Chen JW, Zhou L, Mai KJ, Wu ZX, Li D, Anderson DE, Zhang LB, Li SY, Mi ZQ, He TT, Cong F, Guo PJ, Huang R, Luo Y, Liu XL, Chen J, Huang Y, Sun Q, Zhang XL, Wang YY, Xing SZ, Chen YS, Sun Y, Li J, Daszak P, Wang LF, Shi ZL, Tong YG#, Ma JY. Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin. Nature. 2018 Apr;556(7700):255-258. doi. 10.1038/s41586-018-0010-9. Epub 2018 Apr 4. PubMed PMID. 29618817.
  2. Tong YG*, Shi WF, Liu D, Qian J, Liang L, Bo XC, Liu J, Ren HG, Fan H, Ni M, Sun Y, Jin Y, Teng Y, Li Z, Kargbo D, Dafae F, Kanu A, Chen CC, Lan ZH, Jiang H, Luo Y, Lu HJ, Zhang XG, Yang F, Hu Y, Cao YX, Deng YQ, Su HX, Sun Y, Liu WS, Wang Z, Wang CY, Bu ZY, Guo ZD, Zhang LB, Nie WM, Bai CQ, Sun CH, An XP, Xu PS, Zhang  XL, Huang Y, Mi ZQ, Yu D, Yao HW, Feng Y, Xia ZP, Zheng XX, Yang ST, Lu B, Jiang  JF, Kargbo B, He FC, Gao GF, Cao WC; China Mobile Laboratory Testing Team in Sierra Leone. Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone. Nature. 2015 Aug 6;524(7563):93-6. doi. 10.1038/nature14490. Epub 2015 May 13. Erratum in. Nature. 2015 Oct 22;526(7574):595. PubMed PMID. 25970247.
  3. Zhuang L, Du J, Cui XM, Li H, Tang F, Zhang PH, Hu JG, Tong YG, Feng ZC, Liu W. Identification of tick-borne pathogen diversity by metagenomic analysis in Haemaphysalis longicornis from Xinyang, China. Infect Dis Poverty. 2018 May 7;7(1):45. doi. 10.1186/s40249-018-0417-4. PubMed PMID. 29730989.
  4. Fang H, Feng J, Xu Y, Zhang Y, Zhan Z, Yin Z, Duan X, Gao B, Tong Y, Wang J, Luo Y, Dai E, Zhou D. Sequencing of pT5282-CTXM, p13190-KPC and p30860-NR, and comparative genomics analysis of IncX8 plasmids. Int J Antimicrob Agents. 2018 Apr 18. pii. S0924-8579(18)30114-6. doi. 10.1016/j.ijantimicag.2018.04.012. [Epub ahead of print] PubMed PMID. 29679645.
  5. Wang H, Wan Z, Sun Q, Zhu N, Li T, Ren X, An X, Deng S, Wu Y, Li X, Li L, Li J, Tong Y, Tang S. Second Human Pegivirus in Hepatitis C Virus-Infected and Hepatitis C Virus/HIV-1-Co-infected Persons Who Inject Drugs, China. Emerg Infect Dis. 2018 May;24(5):908-911. doi. 10.3201/eid2405.161162. PubMed PMID. 29664364; PubMed Central PMCID. PMC5938795.
  6. Li B, Feng J, Zhan Z, Yin Z, Jiang Q, Wei P, Chen X, Gao B, Hou J, Mao P, Wu W, Chen W, Tong Y, Wang J, Li B, Zhou D. Dissemination of KPC-2-Encoding IncX6 Plasmids Among Multiple Enterobacteriaceae Species in a Single Chinese Hospital. Front Microbiol. 2018 Mar 19;9:478. doi. 10.3389/fmicb.2018.00478. eCollection 2018. PubMed PMID. 29616001; PubMed Central PMCID. PMC5868456.
  7. Ma Q, Huang Y, Wang J, Xu X, Hawkey J, Yang C, Liang B, Hu X, Wu F, Yang X, Wang J, Li R, Li P, Xie J, Jia L, Wang L, Hao R, Tong Y, Holt KE, Qiu S, Sun Y, Song H. Multidrug-resistant Shigella sonnei carrying plasmid-mediated mcr-1 gene in China. Int J Antimicrob Agents. 2018 Feb 28. pii. S0924-8579(18)30057-8. doi.  1016/j.ijantimicag.2018.02.019. [Epub ahead of print] PubMed PMID. 29501823.
  8. Basharat Z, Yasmin A, He T, Tong Y. Genome sequencing and analysis of Alcaligenes faecalis subsp. phenolicus MB207. Sci Rep. 2018 Feb 26;8(1):3616. doi. 10.1038/s41598-018-21919-4. PubMed PMID. 29483539; PubMed Central PMCID. PMC5827749.
  9. Teng Y, Bi D, Guo X, Hu D, Feng D, Tong Y. Contact reductions from live poultry market closures limit the epidemic of human infections with H7N9 influenza. J Infect. 2018 Mar;76(3):295-304. doi. 10.1016/j.jinf.2017.12.015. Epub 2018 Feb 2. PubMed PMID. 29406153.
  10. Adriaenssens EM, Wittmann J, Kuhn JH, Turner D, Sullivan MB, Dutilh BE, Jang HB, van Zyl LJ, Klumpp J, Lobocka M, Moreno Switt AI, Rumnieks J, Edwards RA, Uchiyama J, Alfenas-Zerbini P, Petty NK, Kropinski AM, Barylski J, Gillis A, Clokie MRC, Prangishvili D, Lavigne R, Aziz RK, Duffy S, Krupovic M, Poranen MM, Knezevic P, Enault F, Tong Y, Oksanen HM, Rodney Brister J. Taxonomy of prokaryotic viruses. 2017 update from the ICTV Bacterial and Archaeal Viruses Subcommittee. Arch Virol. 2018 Apr;163(4):1125-1129. doi. 10.1007/s00705-018-3723-z. Epub 2018 Jan 22. PubMed PMID. 29356990.
  11. Deng YQ, Zhang NN, Li XF, Wang YQ, Tian M, Qiu YF, Fan JW, Hao JN, Huang XY, Dong HL, Fan H, Wang YG, Zhang FC, Tong YG, Xu Z, Qin CF. Intranasal infection and contact transmission of Zika virus in guinea pigs. Nat Commun. 2017 Nov 21;8(1):1648. doi. 10.1038/s41467-017-01923-4. PubMed PMID. 29162827; PubMed Central PMCID. PMC5698318.
  12. Ma L, Yin Z, Zhang D, Zhan Z, Wang Q, Duan X, Gao H, Liang Q, Zhao Y, Feng J, Zhao Y, Tong Y, Dai E, Zhou D. Comparative genomics of type 1 IncC plasmids from Future Microbiol. 2017 Dec;12:1511-1522. doi. 10.2217/fmb-2017-0072. Epub  2017 Nov 15. PubMed PMID. 29140102.
  13. Zhang X, Wang Y, Tong Y. Analyzing Genome Termini of Bacteriophage Through High-Throughput Sequencing. Methods Mol Biol. 2018;1681:139-163. doi. 10.1007/978-1-4939-7343-9_11. PubMed PMID. 29134593.
  14. Li L, Guo X, Zhao Q, Tong Y, Fan H, Sun Q, Xing S, Zhou H, Zhang J. Investigation on Mosquito-Borne Viruses at Lancang River and Nu River Watersheds in Southwestern China. Vector Borne Zoonotic Dis. 2017 Dec;17(12):804-812. doi. 10.1089/vbz.2017.2164. Epub 2017 Oct 30. PubMed PMID. 29083983.
  15. Li H, Zhang PH, Huang Y, Du J, Cui N, Yang ZD, Tang F, Fu FX, Li XM, Cui XM, Fan YD, Xing B, Li XK, Tong YG, Cao WC, Liu W. Isolation and Identification of Rickettsia raoultii in Human Cases. A Surveillance Study in 3 Medical Centers in  Clin Infect Dis. 2018 Mar 19;66(7):1109-1115. doi. 10.1093/cid/cix917. PubMed PMID. 29069294.
  16. Zhao Y, Wang L, Zhang Z, Feng J, Kang H, Fang L, Jiang X, Zhang D, Zhan Z, Zhou D, Tong Y. Structural genomics of pNDM-BTR harboring In191 and Tn6360, and other bla (NDM)-carrying IncN1 plasmids. Future Microbiol. 2017 Nov;12:1271-1281. doi. 10.2217/fmb-2017-0067. Epub 2017 Oct 13. PubMed PMID. 29027482.
  17. Shi L, Liang Q, Feng J, Zhan Z, Zhao Y, Yang W, Yang H, Chen Y, Huang M, Tong Y, Li X, Yin Z, Wang J, Zhou D. Coexistence of two novel resistance plasmids, bla(KPC-2)-carrying p14057A and tetA(A) -carrying p14057B, in Pseudomonas aeruginosa. Virulence. 2017 Oct 4:1-6. doi. 10.1080/21505594.2017.1372082. [Epub ahead of print] PubMed PMID. 28891735.
  18. Zou D, Huang Y, Liu W, Yang Z, Dong D, Huang S, He X, Ao D, Liu N, Wang S, Wang Y, Tong Y, Yuan J, Huang L. Complete sequences of two novel bla (NDM-1)-harbouring plasmids from two Acinetobacter towneri isolates in China associated with the acquisition of Tn125. Sci Rep. 2017 Aug 24;7(1):9405. doi. 10.1038/s41598-017-09624-0. PubMed PMID. 28839253; PubMed Central PMCID. PMC5571222.
  19. Liu ZY, Yu JY, Huang XY, Fan H, Li XF, Deng YQ, Ji X, Cheng ML, Ye Q, Zhao H, Han JF, An XP, Jiang T, Zhang B, Tong YG, Qin CF. Characterization of cis-Acting RNA Elements of Zika Virus by Using a Self-Splicing Ribozyme-Dependent Infectious Clone. J Virol. 2017 Oct 13;91(21). pii. e00484-17. doi. 10.1128/JVI.00484-17. Print 2017 Nov 1. PubMed PMID. 28814522; PubMed Central PMCID. PMC5640849.
  20. Xing S, Zhang X, Sun Q, Wang J, Mi Z, Pei G, Huang Y, An X, Fu K, Zhou L, Zhao B, Tong Y. Complete genome sequence of a novel, virulent Ahjdlikevirus bacteriophage that infects Enterococcus faecium. Arch Virol. 2017 Dec;162(12):3843-3847. doi. 10.1007/s00705-017-3503-1. Epub 2017 Aug 16. PubMed PMID. 28812171.
  21. Teng Y, Liu S, Guo X, Liu S, Jin Y, He T, Bi D, Zhang P, Lin B, An X, Feng D, Mi Z, Tong Y. An Integrative Analysis Reveals a Central Role of P53 Activation via MDM2 in Zika Virus Infection Induced Cell Death. Front Cell Infect Microbiol. 2017 Jul 20;7:327. doi. 10.3389/fcimb.2017.00327. eCollection 2017. PubMed PMID. 28775961; PubMed Central PMCID. PMC5517408.
  22. Shi L, Liang Q, Zhan Z, Feng J, Zhao Y, Chen Y, Huang M, Tong Y, Wu W, Chen W, Li X, Yin Z, Wang J, Zhou D. Co-occurrence of 3 different resistance plasmids in a multi-drug resistant Cronobacter sakazakii isolate causing neonatal infections. Virulence. 2018 Jan 1;9(1):110-120. doi. 10.1080/21505594.2017.1356537. Epub 2017 Aug 16. PubMed PMID. 28771073; PubMed Central PMCID. PMC5955447.
  23. Feng J, Yin Z, Zhao Q, Zhao Y, Zhang D, Jiang X, Wu W, Chen W, Wang H, Song Y, Tong Y, Wang J, Li Y, Zhou D. Genomic characterization of novel IncFII-type multidrug resistant plasmids p0716-KPC and p12181-KPC from Klebsiella pneumoniae. Sci Rep. 2017 Jul 19;7(1):5830. doi. 10.1038/s41598-017-06283-z. PubMed PMID. 28725038; PubMed Central PMCID. PMC5517477.
  24. Yang Y, Cai L, Ma R, Xu Y, Tong Y, Huang Y, Jiao N, Zhang R. A Novel Roseosiphophage Isolated from the Oligotrophic South China Sea. Viruses. 2017 May 15;9(5). pii. E109. doi. 10.3390/v9050109. PubMed PMID. 28505134; PubMed Central PMC5454422.
  25. Jiang T, Jiang JF, Deng YQ, Jiang BG, Fan H, Han JF, Hu Y, Zhuang DM, Kargbo D, An XP, Mi ZQ, Zhao GY, Xin WW, Tan YF, He J, Gao RB, Wang H, Chen C, Wang F, Li CX, Zhao JJ, Cui YJ, Bei ZC, Zhang K, Shang XY, Zhang WH, Pei GQ, Wang YF, Wang W, Shu P, Liu WL, Cheng S, Zhu SY, Kanu A, Kargbo B, Gao B, Tong YG, Fang TY, Cao WC. Features of Ebola Virus Disease at the Late Outbreak Stage in Sierra  Clinical, Virological, Immunological, and Evolutionary Analyses. J Infect  Dis. 2017 Apr 1;215(7):1107-1110. doi. 10.1093/infdis/jix061. PubMed PMID. 28498995.
  26. Xing S, Pan X, Sun Q, Pei G, An X, Mi Z, Huang Y, Zhao B, Tong Y. Complete Genome Sequence of a Novel Multidrug-Resistant Klebsiella pneumoniae Phage, vB_Kpn_IME260. Genome Announc. 2017 May 11;5(19). pii. e00055-17. doi. 10.1128/genomeA.00055-17. PubMed PMID. 28495757; PubMed Central PMCID. PMC5427192.
  27. Jiang X, Yin Z, Yin X, Fang H, Sun Q, Tong Y, Xu Y, Zhang D, Feng J, Chen W, Song Y, Wang J, Chen S, Zhou D. Sequencing of bla(IMP)-Carrying IncN2 Plasmids, and Comparative Genomics of IncN2 Plasmids Harboring Class 1 Integrons. Front Cell Infect Microbiol. 2017 Mar 30;7:102. doi. 10.3389/fcimb.2017.00102. eCollection 2017. PubMed PMID. 28424761; PubMed Central PMCID. PMC5371602.
  28. Zhang Z, Dong Z, Li J, Carr MJ, Zhuang D, Wang J, Zhang Y, Ding S, Tong Y, Li D, Shi W. Protective Efficacies of Formaldehyde-Inactivated Whole-Virus Vaccine and Antivirals in a Murine Model of Coxsackievirus A10 Infection. J Virol. 2017 Jun 9;91(13). pii. e00333-17. doi. 10.1128/JVI.00333-17. Print 2017 Jul 1. PubMed PMID. 28424287; PubMed Central PMCID. PMC5469256.
  29. Liang Q, Yin Z, Zhao Y, Liang L, Feng J, Zhan Z, Wang H, Song Y, Tong Y, Wu W, Chen W, Wang J, Jiang L, Zhou D. Sequencing and comparative genomics analysis of the IncHI2 plasmids pT5282-mphA and p112298-catA and the IncHI5 plasmid pYNKP001-dfrA. Int J Antimicrob Agents. 2017 Jun;49(6):709-718. doi. 10.1016/j.ijantimicag.2017.01.021. Epub 2017 Apr 5. PubMed PMID. 28390961.
  30. Li H, Sheng C, Wang S, Yang L, Liang Y, Huang Y, Liu H, Li P, Yang C, Yang X, Jia L, Xie J, Wang L, Hao R, Du X, Xu D, Zhou J, Li M, Sun Y, Tong Y, Li Q, Qiu S, Song H. Removal of Integrated Hepatitis B Virus DNA Using CRISPR-Cas9. Front Cell Infect Microbiol. 2017 Mar 22;7:91. doi. 10.3389/fcimb.2017.00091. eCollection 2017. PubMed PMID. 28382278; PubMed Central PMCID. PMC5360708.
  31. Zhang Q, Xing S, Sun Q, Pei G, Cheng S, Liu Y, An X, Zhang X, Qu Y, Tong Y. Characterization and complete genome sequence analysis of a novel virulent Siphoviridae phage against Staphylococcus aureus isolated from bovine mastitis in Xinjiang, China. Virus Genes. 2017 Jun;53(3):464-476. doi. 10.1007/s11262-017-1445-z. Epub 2017 Mar 15. PubMed PMID. 28299517.
  32. Xing S, Ma T, Zhang X, Huang Y, Mi Z, Sun Q, An X, Fan H, Wu S, Wei L, Tong Y. First complete genome sequence of a virulent bacteriophage infecting the opportunistic pathogen Serratia rubidaea. Arch Virol. 2017 Jul;162(7):2021-2028. 10.1007/s00705-017-3300-x. Epub 2017 Mar 6. PubMed PMID. 28265773.
  33. Zhang Z, Dong Z, Wei Q, Carr MJ, Li J, Ding S, Tong Y, Li D, Shi W. A Neonatal Murine Model of Coxsackievirus A6 Infection for Evaluation of Antiviral and Vaccine Efficacy. J Virol. 2017 Apr 13;91(9). pii. e02450-16. doi. 10.1128/JVI.02450-16. Print 2017 May 1. PubMed PMID. 28250116; PubMed Central PMCID. PMC5391469.
  34. Lai CC, Wang KY, Chen R, Zhang AJ, Gu HJ, Yin YB, Wang DD, Liu LL, Xing L, Tong YG, Ma ZJ, Yang PH, Wang XL. Characterization of Highly Pathogenic Avian Influenza H5N1 Viruses Isolated from Domestic Poultry in China. Biomed Environ Sci. 2017 Jan;30(1):68-74. doi. 10.3967/bes2017.009. PubMed PMID. 28245902.
  35. Teng Y, Bi D, Xie G, Jin Y, Huang Y, Lin B, An X, Tong Y, Feng D. Model-informed risk assessment for Zika virus outbreaks in the Asia-Pacific regions. J Infect. 2017 May;74(5):484-491. doi. 10.1016/j.jinf.2017.01.015. Epub 2017 Feb 9. PubMed PMID. 28189711.
  36. Zhang X, Guo X, Fan H, Zhao Q, Zuo S, Sun Q, Pei G, Cheng S, An X, Wang Y, Mi Z, Huang Y, Zhang Z, Tong Y, Zhou H, Zhang J. Complete genome sequence of Menghai flavivirus, a novel insect-specific flavivirus from China. Arch Virol. 2017 May;162(5):1435-1439. doi. 10.1007/s00705-017-3232-5. Epub 2017 Feb 7. PubMed PMID. 28175982.
  37. Lv Q, Zhang H, Tian L, Zhang R, Zhang Z, Li J, Tong Y, Fan H, Carr MJ, Shi W. Novel sub-lineages, recombinants and reassortants of severe fever with thrombocytopenia syndrome virus. Ticks Tick Borne Dis. 2017 Mar;8(3):385-390. doi. 10.1016/j.ttbdis.2016.12.015. Epub 2017 Jan 3. PubMed PMID. 28117273.
  38. Xing S, Guo X, Zhang X, Zhao Q, Li L, Zuo S, An X, Pei G, Sun Q, Cheng S, Wang Y, Fan H, Mi Z, Huang Y, Zhang Z, Zhou H, Zhang J, Tong Y. A novel mosquito-borne reassortant orbivirus isolated from Xishuangbanna, China. Virol Sin. 2017 Apr;32(2):159-162. doi. 10.1007/s12250-016-3886-2. PubMed PMID. 28063012.
  39. Teng Y, Bi D, Xie G, Jin Y, Huang Y, Lin B, An X, Feng D, Tong Y. Dynamic Forecasting of Zika Epidemics Using Google Trends. PLoS One. 2017 Jan 6;12(1):e0165085. doi. 10.1371/journal.pone.0165085. eCollection 2017. PubMed PMID. 28060809; PubMed Central PMCID. PMC5217860.
  40. Sun Q, Zhao Q, An X, Guo X, Zuo S, Zhang X, Pei G, Liu W, Cheng S, Wang Y, Shu P, Mi Z, Huang Y, Zhang Z, Tong Y, Zhou H, Zhang J. Complete genome sequence of Menghai rhabdovirus, a novel mosquito-borne rhabdovirus from China. Arch Virol. 2017 Apr;162(4):1103-1106. doi. 10.1007/s00705-016-3188-x. Epub 2016 Dec 20. PubMed PMID. 28000049.
  41. Cai M, Wang C, Li Y, Gu H, Sun S, Duan Y, Lai C, Wang K, Yang X, Xing L, Zhang P, Wang Z, Zhang S, Guo X, Liu S, Tong Y, Wang X, Yang P. Virus-like particle vaccine by intranasal vaccination elicits protective immunity against respiratory syncytial viral infection in mice. Acta Biochim Biophys Sin (Shanghai). 2017 Jan;49(1):74-82. doi. 10.1093/abbs/gmw118. Epub 2016 Dec 14. PubMed PMID. 27974288.
  42. Zhao T, Qian YH, Chen SH, Wang GL, Wu MN, Huang Y, Ma GY, Fang LQ, Gray GC, Lu B, Tong YG, Ma MJ, Cao WC. Novel H7N2 and H5N6 Avian Influenza A Viruses in Sentinel Chickens. A Sentinel Chicken Surveillance Study. Front Microbiol. 2016 Nov 16;7:1766. eCollection 2016. PubMed PMID. 27899915; PubMed Central PMCID. PMC5110548.
  43. Qu Y, Huang Y, Liu D, Huang Y, Zhang Z, Mi Z, An X, Tong Y, Lu J. High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion. Can J Infect Dis Med Microbiol. 2016;2016:8594107. Epub 2016 Oct 13. PubMed PMID. 27818694; PubMed Central PMCID. PMC5081459.
  44. Liu Y, Mi L, Mi Z, Huang Y, Li P, Zhang X, Tong Y, Bai C. Complete Genome Sequence of IME207, a Novel Bacteriophage Which Can Lyse Multidrug-Resistant Klebsiella pneumoniae and Salmonella. Genome Announc. 2016 Oct 27;4(5). pii. e01015-16. doi. 10.1128/genomeA.01015-16. PubMed PMID. 27789630; PubMed Central PMCID. PMC5084854.
  45. Liu W, Sun FJ, Tong YG, Zhang SQ, Cao WC. Rift Valley fever virus imported into China from Angola. Lancet Infect Dis. 2016 Nov;16(11):1226. doi. 10.1016/S1473-3099(16)30401-7. PubMed PMID. 27788984.
  46. Bai CQ, Mu JS, Kargbo D, Song YB, Niu WK, Nie WM, Kanu A, Liu WW, Wang YP, Dafae F, Yan T, Hu Y, Deng YQ, Lu HJ, Yang F, Zhang XG, Sun Y, Cao YX, Su HX, Sun Y, Liu WS, Wang CY, Qian J, Liu L, Wang H, Tong YG, Liu ZY, Chen YS, Wang HQ, Kargbo B, Gao GF, Jiang JF. Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)-Sierra Leone, 2014. Clin Infect Dis. 2016 Nov 15;63(10):1288-1294. Epub 2016 Aug 23. PubMed PMID. 27553371.
  47. Liu Y, Mi Z, Niu W, An X, Yuan X, Liu H, Wang Y, Feng Y, Huang Y, Zhang X, Zhang Z, Fan H, Peng F, Li P, Tong Y, Bai C. Potential of a lytic bacteriophage to disrupt Acinetobacter baumannii biofilms in vitro. Future Microbiol. 2016 Oct;11:1383-1393. Epub 2016 Aug 18. PubMed PMID. 27538011.
  48. Ni M, Chen C, Qian J, Xiao HX, Shi WF, Luo Y, Wang HY, Li Z, Wu J, Xu PS, Chen SH, Wong G, Bi Y, Xia ZP, Li W, Lu HJ, Ma J, Tong YG, Zeng H, Wang SQ, Gao GF, Bo XC, Liu D. Intra-host dynamics of Ebola virus during 2014. Nat Microbiol. 2016 Sep 5;1(11):16151. doi. 10.1038/nmicrobiol.2016.151. PubMed PMID. 27595345.
  49. Li XF, Dong HL, Huang XY, Qiu YF, Wang HJ, Deng YQ, Zhang NN, Ye Q, Zhao H, Liu ZY, Fan H, An XP, Sun SH, Gao B, Fa YZ, Tong YG, Zhang FC, Gao GF, Cao WC, Shi PY, Qin CF. Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates. EBioMedicine. 2016 Oct;12:170-177. doi. 10.1016/j.ebiom.2016.09.022. Epub 2016 Sep 23. PubMed PMID. 27693104; PubMed Central PMCID. PMC5078627.
  50. Butt AM, Nasrullah I, Qamar R, Tong Y. Evolution of codon usage in Zika virus genomes is host and vector specific. Emerg Microbes Infect. 2016 Oct 12;5(10):e107. doi. 10.1038/emi.2016.106. PubMed PMID. 27729643; PubMed Central PMCID. PMC5117728.
  51. Sun F, Zhou D, Sun Q, Luo W, Tong Y, Zhang D, Wang Q, Feng W, Chen W, Fan Y, Xia P. Genetic characterization of two fully sequenced multi-drug resistant plasmids pP10164-2 and pP10164-3 from Leclercia adecarboxylata. Sci Rep. 2016 Sep 23;6:33982. doi. 10.1038/srep33982. PubMed PMID. 27658354; PubMed Central PMCID. 
  52. Feng W, Zhou D, Wang Q, Luo W, Zhang D, Sun Q, Tong Y, Chen W, Sun F, Xia P. Dissemination of IMP-4-encoding pIMP-HZ1-related plasmids among Klebsiella pneumoniae and Pseudomonas aeruginosa in a Chinese teaching hospital. Sci Rep. 2016 Sep 19;6:33419. doi. 10.1038/srep33419. PubMed PMID. 27641711; PubMed Central PMCID. PMC5027574.
  53. Cheng S, Xing S, Zhang X, Pei G, An X, Mi Z, Huang Y, Tong Y. Complete Genome Sequence of a New Enterococcus faecalis Bacteriophage, vB_EfaS_IME197. Genome Announc. 2016 Sep 15;4(5). pii. e00827-16. doi. 10.1128/genomeA.00827-16. PubMed 27634987; PubMed Central PMCID. PMC5026427.
  54. Li H, Sheng C, Liu H, Liu G, Du X, Du J, Zhan L, Li P, Yang C, Qi L, Wang J, Yang X, Jia L, Xie J, Wang L, Hao R, Xu D, Tong Y, Zhou Y, Zhou J, Sun Y, Li Q, Qiu S, Song H. An Effective Molecular Target Site in Hepatitis B Virus S Gene for Cas9 Cleavage and Mutational Inactivation. Int J Biol Sci. 2016 Aug 5;12(9):1104-13. doi. 10.7150/ijbs.16064. eCollection 2016. PubMed PMID. 27570484; PubMed Central PMCID. PMC4997054.
  55. Shi W, Zhang Z, Ling C, Carr MJ, Tong Y, Gao GF. Increasing genetic diversity of Zika virus in the Latin American outbreak. Emerg Microbes Infect. 2016 Jul 6;5:e68. doi. 10.1038/emi.2016.68. PubMed PMID. 27381219; PubMed Central PMCID. PMC4972906.
  56. Fan J, Zeng Z, Mai K, Yang Y, Feng J, Bai Y, Sun B, Xie Q, Tong Y, Ma J. Preliminary treatment of bovine mastitis caused by Staphylococcus aureus, with trx-SA1, recombinant endolysin of S. aureus bacteriophage IME-SA1. Vet Microbiol. 2016 Aug 15;191:65-71. doi. 10.1016/j.vetmic.2016.06.001. Epub 2016 Jun 6. PubMed PMID. 27374909.
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